An article making the rounds is "Fox News Viewers Know Less Than People Who Don't Watch Any News", Huffington Post, 2011-11-21.
However, be sure to follow the links to the Fairleigh Dickinson report. There is a surprise about who is best informed.
It also depends on when you ask what questions. PolitiFact gave Jon Stewart a mostly false reading on its Truth-O-Meter for his claim that Fox News viewers are the most misinformed.
My take is that even though Fox News is near the bottom with a few other sources, the most misinformed are those who don't use any of the standard sources of information. And there are far too many of those.