And I don't mean resignations assuming responsibility for the collapse of a bridge. Where are the high-level resignations when "something went wrong during my watch"? Once upon a time, British or Japanese ministers would resign if things fell apart during their term, regardless of how culpable they may have been.
How many high-level resignations can you remember? Nixon, of course, but he went out with a long drawn-out fight? Most resignations, other than fatigue, occur because someone disagrees with his or her boss' policies. Others are forced out when popular opinion turns against them and the President asks for the resignation; the resignee rarely offers to resign until asked. For example, John Bolton as Ambassador to the U.N. or Donald Rumsfeld as Secretary of Defense.
We won't see Minnesota Lt. Gov./Commissioner of Transportation Carol Molnau or U.S. Attorney General Alberto Gonzales admitting that they let things get out of hand or that they didn't monitor things as thoroughly as they should have. It isn't just Republicans who won't admit responsibility for bad policies. Robert McNamara, Lyndon Johnson's Secretary of Defense, didn't see the "light at the end of the tunnel" until decades after the Viet Nam war ended.